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Spain, late 1980s. Newcomer Sara tries to fit in with the other teens in this tight-knit small town in the province of Tarrgona. If only she were more like her extroverted best friend, Rebe. They go out one night at a nightclub, on the way home, they come upon a little girl holding a doll, dressed for her first communion. And that's when the nightmare begins.。一架载有最新生化武器样本的军用飞机坠毁宾西法尼亚州某小镇附近的山上，破碎的生物样本流入水源。凡饮用过感染水源的人或中毒而死，或狂性大发自残自杀。派科姆上校（Lloyd Hollar 饰）及怀茨医生（Richard France 饰）奉总统之命，分别率领军队和医疗组赶赴小镇，希图控制病毒蔓延。 然而病毒扩散极为迅速，小镇已到不可救药的地步。华府作出决定，将用核武器彻底摧毁小镇以及被感染的人群，任何企图逃跑之人格杀勿论。为了生存而战战兢兢的人们，更要面对即将到来的毁灭厄运……。